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» Research Directions

  • Genetic biodiversity, molecular phylogeny,  human and animal genotyping using microsatellite and mDNA markers: establishing phylogenetic correlations in the context of the biodiversity in vertebrates and in-vertebrates in Romania; genetic characterization of productive parameters for animals of economic interest; molecular characterization and traceability of animal and animal products . 
  • Molecular characterization of various human pathologies: cancer (colon, prostate, mammary and ovarian), dystrophinopathies, ageing, autoimmune diseases, pulmonary fibrosis by: cell signalling; population screening; microsatellite instability (MSI), allelic imbalance (AI) and loss of heterozygosity (LOH); cytotoxic and cytoprotective effects of certain natural and synthesis compounds on primary culture cells and cell lines.
  • Molecular toxicology:  effects of various xenobiotics and nanoparticles in the environment on animal systems (oxidative stress; senescence; apoptosis; Heat shoc proteins expression by transcriptional and translational approaches; screening gene expression modulation - cDNA array, Real-Time RT-PCR; proteom profile assessment).
  • Tissular engineering, biomaterials, biocompatibility: new culture biotechnologies (single layer/3-D holders) of human cells for medical use; biocompatibility studies (viability, proliferation and cell adhesion, organization of the cytoskeleton, turnover of extracellular matrix etc.) of certain new materials to be used in bone and dental implantology.
  • Molecular biotechnologies: biologically active compounds of microbial and plant origin with antitumoral and prebiotic activity; obtaining biofuels; GMO and plant protein identification in food products.
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Splaiul Independentei
no. 91-95, sector 5,
postal code 050095,
BUCHAREST, ROMANIA
Phone / fax: +40 21 3181575
Phone: +40 21 3181567
Web: dbbm.bio.unibuc.ro